Bdellovibrio bacteriovorus is a bacterium which preys upon and kills Gram- negative bacteria, including the zoonotic pathogens Escherichia coli and Salmonella. Bdellovibrio bacteriovorus is a small, curved, and highly motile Gram-negative bacteria approximately to μm wide and to μm long. Bdellovibrio bacteriovorus is a predator bacterial species found in the environment and within the human gut, able to attack Gram-negative prey. Cystic fibrosis.
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A Microbial Biorealm page on the genus Bdellovibrio bacteriovorus. Bdellovibrios were discovered by Stolp and Petzhold inin an attempt to isolate bacteriophage from soil bacteriovodus. Stolp and Petzhold observed unique plaques in their samples that took several days to develop and continued to grow for over a week, instead of plaques caused by bacteriophages that would appear within hours.
A closer inspection of the plaques under a light microscope revealed cells that were small, highly motile, and vibrio-shaped. These cells were Bdellovibrios. After the discovery of Bdellovibrios further observations revealed many interesting and unique properties.
One property that makes Bdellovibrios interesting is that it is a parasite to other Gram-negative bacterias.
Bdellovibrios have biphasic life-cycles that include an attack phase, and a free living and mobile phase. Bdellovibrio bacteriovorus is a small, curved, and highly motile Gram-negative bacteria approximately 0.
Bdellovibrio bacteriovorus : A future antimicrobial agent?
The sequencing of the B. The complete genome consists of a single circular chromosome that is 3, nucleotides long. Of the large number of proteins that the B. These enzymes are necessary for B. Some of these enzymes need to be secreted out of B. Therefore, the genome of B. Other than encoding for degradative enzymes and transport systems, the chromosome also contains multiple biosynthetic gene clusters that are necessary for the formation of the flagella and pilus.
These gene clusters are essential for the motility B.
Bdellovibrio – Wikipedia
However, the organism sheds its flagellum once it makes irreversible contact with its prey cell suggesting that the flagellum is not required for it to grow. The general cell structure of B. The unique biphasic life-cycle of B.
In the free-living or mobile phase, B. During the mobile phase, most of the metabolic activity is involved in motility and prey detection. A large variety of metabolic activities occur during this phase.
In the attack phase, B. After entry into the prey cell, B. The degradation of the inner membrane causes the prey cell to become a bdelloplast, host cell of Bdellovibrios with a stable spherical structure, and also the destruction of the host cell’s ability to generate energy.
The metabolism of B. One of these areas is that B. The reason for this is that B. It can break down or rearrange these precursors for the biosynthesis of homologous polymers.
The uptake of nucleoside monophosphates and glycerol phoshphates greatly reduces the amount of energy that B. There has also been evidence that B. Experiments have shown that the energy efficiency of B. They have been found in soil samples, rhizosphere of plant roots, rivers, oceans, sewage, intestines and feces of birds and mammals, and even in oyster shells and the gills of crabs.
Its optimal temperature is between C, making B. It can live in a range of salinity and is resistant to pollution of its environment. It seems that the rich environment of biofilms supply B. Research has shown that B. Coli biofilm that is grown on stainless steel.
It is a known pathogen to Gram-negative bacteria, making it a possible biocontrol agent to many human pathogens. The major applications of B. The use of B. Currently, the main field of research with B. Many experiments are performed to test how it specifically recognizes its prey. There is also research on how B. It is also highly possible that a slight change in its genetic code can allow B. When introduced to multiple preys, B.
This research showed that B. Bdellovibrio make fast food of gram-negative bacteria. Edited by Hiu Chengstudent of Rachel Larsen. From MicrobeWiki, the student-edited microbiology resource. This student page has not been curated. A Microbial Bdelloivbrio page on the genus Bdellovibrio bacteriovorus Contents. Retrieved from ” https: Personal tools Log in.