Comparative hemorheology, in Handbook of Hemorheology and Hemodynamics, eds. O. K. Baskurt, M. R. Hardeman, M. W. Rampling, and. Article · January. Handbook of Hemorheology and Hemodynamics – Ebook download as PDF File .pdf), Text File .txt) or read book online. significantly contribute to hemorheological variations in diseases and in certain extreme physiological properties. KEYWORDS: Hemorheology, hemodynamics, viscosity, erythrocyte deformability, Handbook of Engineering. New York.
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With respect to hemorheology, the new book successfully updates developments and advances in the flow properties of human blood cells microrheology. Handbook of Hemorheology and Hemodynamics.
Description This publication primarily focuses on the macro- and micro-rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, handook on the microvascular aspects of hemodynamics. This early understanding of blood rheology that dominated the first several decades of 20 th century was clearly described in the famous publication of Whittaker and Winton . In turn, these stimuli trigger a response that is mediated by the release of a number of autocrine and paracrine substances.
However, due to experimental difficulties associated with blood coagulation he was unsuccessful with these attempts, and thereafter turned to simpler fluids such as water and oil to hemodjnamics his well-known equation . Conversely, it is difficult to measure the in-vivo hemodynamic parameters.
Handbook of Hemorheology and Hemodynamics Oguz K. Table 1 presents a classification of hemorheological alterations based upon the considerations described above. It also affects the efficiency with which cells are brought into contact with the wall because margination in the flow depends on the concentration of the red cells and their flow-dependent tendency to aggregate .
Abstract The reversible aggregation of human red blood cells RBC continues to be of interest in the field of hemorheology , in that RBC aggregation is abd major determinant of the in vitro rheological properties of blood. Because the flow is time varying, pressure-flow relations are a function of both the shear viscosity and the shear elasticity of the blood.
In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics.
Ebook: Handbook of Hemorheology and Hemodynamics
All of these factors are themselves subject to variation according to a number hemorheilogy short-term and long-term biological control mechanisms. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress.
This approach for calculating apparent viscosity using pressure drop and flow rate data measured in vivo has been used by other investigators under various conditions hhemorheology in different experimental settings [2, 3].
The experiments underlying this formulation were conducted using simple fluids and the viscosity concept was introduced in the equation as a constant, being directly proportional to flow resistance. However, special instruments developed in the last few decades and dedicated to the measurement of various hemorheological parameters e. Xnd general fluid mechanical procedure used to predict how a fluid flows in response to forces involves three steps: In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics.
Basic Principles of Hemodynamics. Finally, some general practical hemorheological laboratory techniques are described. The rate of motion of the cells before capture and the shear forces acting on them during adhesion critically control the efficiency of attachment. This overview is designed to describe the physiology and pathophysiology of hemorheological parameters during the fetal and neonatal period. It is necessary to know that the hemorheological profile of an animal cannot be judged by a single rheological value, but must be considered as part of the cardiovascular system in which the blood is flowing.
The contribution of these factors to blood rheology has been detailed in previous chapters Chapters II.
In this chapter, this procedure will be illustrated for specific applications to blood. This publication primarily focuses on the macro- and micro- rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects hdmorheology hemodynamics. A welcome feature of the handbook is that it includes a chapter on comparative hemorheology, showing that the rheological properties of red cells vary widely among the animal species, thus shedding light on the process of adaptation to a specific environment or lifestyle, and a chapter on neonatal and fetal blood rheology showing the considerable adaptation processes in play at birth and in infancy and childhood.
IOS Press- Medical – pages. Recently, however, developments in optics and electronics have resulted in various techniques for measuring these hemodynamic parameters, with some techniques commercially available.
Viscoelasticity of Human Blood. This was an oversimplification for blood flow and experimental work in the early ‘s revealed that blood viscosity could not be represented with a constant, but rather depended on flow conditions i. Peculiar rheologic properties of blood appear to play an important role in the maintenance of high blood flow conditions in spite of very low blood pressure in the fetus and neonate . This is done by use of the physical principle known as the conservation of momentum, and results in equations which relate the forces to velocity gradients.
Physico-chemical factors that influence leukocyte deformation are then described, and the impact of flow resistance on normal and pathological microcirculation is considered.
The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively.
Thus, enhanced RBC aggregation may not always be related to plasma composition changes, but can co-exist with plasma viscosity alterations.
Account Options Sign in. Van Leeuwenhoek was far ahead of his contemporary scientists, and although the existence and importance of blood circulation was recognized years later i. Thus it is not surprising that the mechanisms of blood rheology alterations are also related to these factors.
In order to understand this system, it is helpful to start by considering the mechanics of fluid flow through a single tube with a uniform cylindrical cross-section. Abstract The factors that determine the rheological behavior of hemodyynamics, a two-phase fluid, include the relative volume of each phase as reflected by the hematocrit value, plasma composition and the properties of cellular elements.
The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. Because of the importance of the mechanical properties of resting and hemodyna,ics leukocytes in the physiology and pathology of the microcirculation, they have been widely studied using rheological techniques.
The viscoelasticity of blood has a direct effect on the propagation of the pulse throughout the arterial system . Inages before there was any concept of blood viscosity, it was appreciated by Anthony van Leeuwenhoek Delft, the Netherlands that red blood cells RBC have to deform in order to negotiate capillary passages . The heartbeat of beats per minute gives a fundamental Fourier component of 1 to 2 Hz. Abstract The circulatory system consists of a pump the heart and an extensive, highly branching system of tubes blood vessels containing a fluid blood with specialized capabilities for the transport of oxygen, nutrients, many other substances and heat.
This publication primarily focuses on the macro- and micro-rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects qnd hemodynamics.
Handbook of Hemorheology and Hemodynamics – Google Books
This rate of circulation is determined by the driving pressure generated by the heart, by the geometrical resistance offered by hemorbeology vasculature and by the flow properties of the blood. The circulatory system consists of a pump the heart and an extensive, highly branching system of tubes blood vessels containing a fluid blood with specialized capabilities for the transport of oxygen, nutrients, many other substances and heat.
As a guest user you are not logged in or recognized by your IP address. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. Understanding of hemodynamics was greatly enhanced by Poiseuillewho developed a relation between flow rate and pressure Poiseuille’s law.