and pharmacological properties of Kigelia africana (Lam.) Balmkheera, Isopinnatal, Kigelin, Chemical constituents, Medicinal properties. Objective: Kigelia africana, a tropical tree, which has long been used in African . Analytical grade solvents (Fischer chemicals) were used for isolation and. cancer with drugs (pharmacotherapy) or with chemical compounds ( chemotherapy) in family comprises 21 species, of which Kigelia africana. (Lam. ) Benth is.

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Fetal growth in rats treated with lapachol. Kushi L, Giovannucci E. Akunyili D, Houghton P.

Constituents of Kigelia pinnata. The ethanolic stem bark extract showed strong analgesic and anti-inflammatory activities in a study. The mixture containing 2. Though a large number of plants worldwide show strong antioxidant activities Baratto et al. The antioxidant potential of the oil was compared to that of ethyl acetate and methanol extracts of the root. The plant is endemic in the south, central and West Africa Burkill, ; Olatunji and Atolani, Literature compilation of the constituents of different collections of Kigelia africana fruits Click here to view.

The total phenolic content was also found to be higher in KPRE at 0. Singapore Journal of Scientific Research, 2: Isolation of glanduloside, D-mannitol and hentriacontane from anticharis Gladulosa Aschers.

The in vitro antioxidant activities of the plant extracts Figure 5 Fig. Polyphenols and disease risk in epidemiologic studies. Species that contain lapachol and several biogenetically related naphthoquinones e. Increasing absorbance indicates an increase in reductive ability.

Antinociceptive and antiedematogenic properties and acute toxicity of Tabebuia avellanedae Lor. The presence of phytol in brown and blue-green algae and its relationship to evolution. Bioactive compounds in nutrition and health-research methodologies for establishing biological function: The hexanes extract caused inhibition of the opportunistic yeast; Cryptococcus neoformans Pinh. Constituents, bioactivity, and reflection on composition disparities. The biological importance and toxicity of elaidic acid, a trans fatty acid have remained controversial.


The extract was decanted, filtered and concentrated under reduced pressure using rotary evaporator to afford mg of a yellow oil which was coded KPRH.

New Constituents of Kigelia pinnata Leaves – SciAlert Responsive Version

Lately, it has been reported that incorporation of trans fatty acids into the phospholipids of the membranes affected its properties and mainly the activity of enzymes attached to the membrane, in fact, in recent times a positive relation has been established between allergic diseases and trans fatty acid consumption Kritchevsky, [ 26 ]; Stender and Dyerberg, [ 49 ].

The relative percentages of the identified compounds are listed in Table 1. KPRM showed the peak activity at 0. Gazz Chim Ital ; Phytochemical screening of the plant extracts A small portion of the dry extract was used for the phytochemical screening for compounds including tannins, phlobatannins, flavonoids, terpenoids, alkaloids, cardiac glycosides, anthraquinone, saponins, and steroids in accordance with methods described by Harborne [ 21 ]Trease and Evans [ 50 ] and Sofowora [ 48 ] with minor modifications.

Dietary trans kiigelia acids affect docosahexaenoic acid concentration in plasma and liver but not brain of pregnant and fetal rats. Deletion of the cyclin-dependent kinase-4 inhibitor gene inmultiple human cancers. The leaves were dried at room temperature and blended into powder. Antiinflammatory activity of the fruit of Kigelia pinnata DC. Forty three fractions were kielia and combined into eight groups after appropriate comparison of the TLC profile.


Wherever, the tree grows it is usually evergreen especially in places where rainfall occurs throughout the year, but deciduous in places of long dry season.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

The final isolation process involved a preparative TLC separation technique. It is due to the presence of high content of phenolics, which could be the most effective in protecting the body against various oxidative stressors.

Hexane, petroleum spirit, dichloromethane, ethyl acetate, methanol and ethanol used were analytical, while silica gel F and vanillin spray reagent were obtained from the chemical store of the Department of Chemistry, University of Ilorin, Nigeria.

J Agric Food Chem. Am J Clin Nutr. The Bignoniaceae family is noted for the occurrence of iridoids, naphthoquinones, flavonoids, terpenes, tannins, steroids, coumarins, saponins and caffeic acid in the fruits, stem, leaves and roots Akunyili and Houghton, [ 2 ]; Houghton et al.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

Structures of verbascoside and orobanchoside, caffeic acid sugar esters from Orobanche rapum-genistae. Special attention may have to be paid to the extraction method. Minor iridoid and phenol glycosides of Picrorhiza kurrooa. The extracts were stored in a cool dark place until further analysis. Fractionation scheme for K. The tree grows on riverbanks, wet areas along streams and on flood plains of Nigeria, Cameroon, Kenya, Guinea and Senegal.